Endocrine Abstracts

Osteoporosis is a debilitating condition that can be prevented by timely detection and treatment. Detection requires referral for dual energy X-ray absorptiometry (DXA) that depends on risk factors. We estimated the importance of risk factors for a T-score of <−2.5 measured by spine and hip DXA in all men and women referred from general practice for a DXA scan at Aalborg University Hospital during a 3 years period. Risk factors were assessed by questionnaire...

Introduction: Iodine deficiency is a significant global health issue of various severity depending on the age of the deficiency. The foetal period is the most critical stage in life, negatively impacting the brain and neurodevelopment. Hence, the developing foetus is a crucial issue, and the present study focussed on iodine nutrition among pregnant women from the Faroe Islands. The need for iodine increases in pregnancy, and the recommended target for median urinary iodine con...

Introduction: Iodine nutrition is critical for human health. In recent years the main focus was on the developing brain during pregnancy. In addition, iodine nutrition is essential for growth and development during adolescence. Iodine nutrition was recently low within the recommended range among adult Faroese living on local, iodine-rich marine food items. Dietary habits among young generations are drifting away from local foods, and this raises a concern that led us to perfor...

Background: Morbidity and mortality are associated with thyroid hormone levels in populations. This has invited a debate on what is the better parameter for assessment of thyroid function: the controlling hormone thyrotropin (TSH) or peripheral thyroid hormone measurements (thyroxine (T4) and triiodothyronine (T3)).Aim: To assess the ability of TSH and total T4 (TT4) to discriminate between subtle differences in thyroid function.Me...

Objectives: The Danish population was previously iodine deficient with regional differences, and a mandatory iodine fortification of salt was introduced more than 20 years ago. Despite iodine fortification and frequent use of iodine-containing supplements, the iodine status in Danish pregnant women was insufficient when evaluated in 2012 (median urinary iodine concentration (UIC): 101 µg/l). From July 1, 2019 the authorities implemented a mandatory increase from 13 to 20 ...

Objective: The aim of this study was to examine the urinary iodine concentrations (UIC) in an adult population in the Faroe Islands. Iodine status in the adult population assumed to be sufficient due to the high frequency of seafood consumption1 although UIC has not been investigated previously in the Faroe Islands. World Health Organization recommends monitoring iodine status in all populations. Iodine nutrition is a key determinant of thyroid disease risk<p class="abstex...

Background: Iodine nutrition relies on dietary intake. Marine foods are iodine rich, and they contributed markedly to the iodine intake among populations in Greenland. However, dietary habits are drifting away from the traditional diet dominated by iodine rich marine foods such as seal, whale, and seabirds. This led us to monitor iodine nutrition among populations in Greenland.Methods: Cohort studies were conducted in 1998, 2008, and 2018 including 50-69...

Introduction: Iodine is essential for thyroid funciton and severe deficiency adversely affects the developing brain. A raised and sufficient intake is particularly important during the pregnancy. Iodine sources include sea foods and sea salt, and it is available as a dietary supplement. The former was previously important to the Faroses diet but the intake of traditional Faroses foods is decreasing with at likely parallel influence on the iodine intake. Currently, there is no ...

Objectives: Measurement of TSH-receptor antibodies (TRAb) in hyperthyroid, pregnant women is an important tool when distinguishing between the autoimmune Graves’ disease and the physiological gestational hyperthyroidism. Evidence to support a cut-off for TRAb in early pregnancy is needed along with information on the frequency and follow-up of TRAb-positive as opposed to TRAb-negative hyperthyroidism.Methods: Within the North Denmark Region Pregnanc...

Objective: Physiological alterations challenge the assessment of maternal thyroid function in pregnancy. It remains uncertain how the reference ranges vary by week of pregnancy, and how the classification of maternal thyroid disease vary by analytical method and type of thyroid function test.Method: Consecutively collectedserum samples from 6.282 pregnant women in the North Denmark Region, 2011–2013, were used for the measurement of thyrotropin (TS...